Our Epilepsy Team
First let's do a little introduction
Epilepsy is one of the most common neurological conditions in the world. More than 65 million people in the world are affected, from it around the world and statistics show that on average one in 20 people will suffer from some type of these crises at some point in their life (although this does not necessarily mean a diagnosis of epilepsy). While epilepsy is most commonly diagnosed in children and people over the age of 65, it can occur to anyone and at any age, with no gender or ethnicity preferences, making it highly unpredictable. It is characterized by disorders in the activity of the brain, which cause seizures, periods of unusual behaviors or feelings, sensations and sometimes loss of awareness.
What is behind
According to the International League Against Epilepsy (ILAE), there are more than 30 types of epileptic syndromes, including some more severe and debilitating forms often seen in very young children in the first months of life such as Ohtahara syndrome, Dravet syndrome and West syndrome. The causes of these diseases are varied and complex. They can result from brain damage caused by injuries such as trauma suffered due to an accident or a problematic birth, brain tumors, viral and bacterial infections such as meningitis or from genetic factors.
After the discovery of the first gene associated with epilepsy in 1995, there have been numerous advances to understand the genetics of epilepsy in fact in 2019 more than 140 genes or loci were associated on the OMIM databases. The genetic mechanisms that contribute to epilepsies are also being studied continuously, for example a repeated expansion of nucleotides has been identified as the cause of a myoclonic familial epilepsy and in some cases somatic mosaicism has also been found to cause focal epileptogenic lesions.
The way to Precision Medicine
Current drug therapies offer a range of about 30 antiepileptic drugs (AEDs) that aim to prevent the occurrence of epileptic seizures, but do not cure epilepsy. With the prescription of the correct antiepileptic drugs, almost 70% of patients are able to control their seizures, however these are not without side effects and adverse reactions to this type of drugs vary greatly from individual to individual. Thanks to new insights into pharmacogenetics, a detailed understanding of the patient's genome offers the promise of more targeted treatment based on his/her genotype.
Analyze your entire DNA with a Stripe2be test
At Stripe2Be we provide Whole Genome Sequencing (WGS), analyzing 100% of your DNA. It is the most comprehensive, detailed type of genetic test available. We break down your WGS data into 5 easier-to-read reports which are all about your individual Stripes.
How do you guarantee my privacy?
Privacy is a fundamental human right. At Stripe2Be, it's also our core value! These are the actions we have taken to ensure your privacy:
1) We rigorously carry out all our activities in our laboratories and offices, following strict protocols and ensuring the best result. As a Whole Genome Sequencing company we only share reports with the real test owner.
2) We are fully compliant with the General Data Protection Regulation (GDPR).
3) We have created a cloud database infrastructure on Amazon Web Services (AWS) to guarantee you the highest level of security.
4) If you do not want us to keep your data (personal and genomic), we will delete your data. It is sufficient to request the deletion of personal data at any time by sending an email to firstname.lastname@example.org.
Is your service available in my country?
We ship our tests worldwide with Next-day free shipping and returns.
Are Stripe2be tests suitable for children?
Whole genome Sequencing
The Stripe2be test is available for any type of person, it is safe, painless and quick to perform. Stripe2be and our team of variant curators take these issues very seriously and always provide the best service for all needs, carrying out the most thorough analysis process and ensuring total data privacy.
For any other questions regarding this policy, please do not hesitate to contact our customer support team.
How long does it take to sequence my genome?
Sequencing Turnaround time
It depends on the turnaround time you chose at checkout (2 weeks or 8 weeks). Within 2 weeks or 8 weeks of us receiving your sample kit at our laboratory, your sample will be analysed, and your results will be delivered securely online. You will be notified by email when your results are ready.
How secure is your data?
Privacy is also a fundamental human right, for Stripe2be it is also the founding value. We are fully compliant with the new European regulation on privacy (General Data Protection Regulation). We have built a database cloud infrastructure on Amazon Web Services (AWS) to guarantee you the highest level of security.